Curriculum Vitae

Personal details

Johan van Soest

Brightlands Institute for Smart digital Society (BISS)
Faculty of Science and Engineering
Maastricht University
Maastricht, The Netherlands

Email: j.vansoest at maastrichtuniversity.nl

Work experience

June 2021 - Present Assistant professor
Brightlands Institute of Smart digital Society (BISS), Maastricht University
March 2020 - June 2021 Postdoctoral researcher
Brightlands Insititute of Smart digital Society (BISS), Maastricht University
June 2017 - March 2020 Postdoctoral researcher
1 Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre
2 Institute of Data Science, Maastricht University
June 2017 - present Chief Technical Officer and co-founder of Medical Data Works B.V.
Translate research software into clinical products and practice.
June 2016 - September 2016 Visiting Research Scholar, University of Toronto
Setting up a collaborating infrastructure to perform distributed machine learning on routine clinical datasets (nightly extraction of datasets). Special focus on cohort differences, and when to decide to re-train a prediction model.
July 2014 - September 2014 Visiting Research Scholar, University of Sydney
Setting up a collaborating infrastructure (equally as used in the VATE project) to perform distributed machine learning on routine clinical datasets (nightly extraction of datasets). Main reason to choose distributed machine learning is to keep datasets (and therefore patient information) in the hospitals. Instead, the candidate prediction models are sent to the local centers, rather than centralizing datasets.
August 2013 - June 2017 PhD Student, Maastro Clinic.
Involved in several projects aiming to make healthcare data interoperable, and to implement federated learning technologies to perform data analysis on remote interoperable data.
August 2012 - December 2020 Technical Application Management, Maastro Clinic.
Technical application manager for the CancerData.org image archive, and the CTMM-TraIT BioMedical Image Archive (bmia.nl). Both archives are used to store research-related DICOM information, which is anonymized before leaving the local hospital.
November 2011 - July 2012 Scientific Research Project (SRP) / Master thesis for the Master Medical Informatics.
Subject: Score Engineering - Optimizing the SOFA score for predicting intensive care mortality using evolutionary strategies.
Description: Scoring systems are ubiquitous in medicine, especially in intensive care departments. We developed an evolutionary algorithm in R to optimize the SOFA score for mortality prediction. Evaluation of newly defined scoring schemes was performed using (bootstrapped) area under ROC (AUC), Brier score, and Hosmer-Lemeshow C statistic.
January 2011 - July 2011 Internship at the Academic Medical Center, Amsterdam. Dept. of Medical Informatics collaborating with dept. of Geriatrics.
Identification of risk factors for recurring falls in elderly patients, comprising of two tasks:
1.: Development of a clinical registry system for medical process control and data collection for research purposes.
2.: Analysis of collected data to identify risk factors for recurring falls using statistical analysis. Furthermore, automation of medication name correction using string similarity measures.
February 2009 - July 2009 Graduation Internship Bachelor of ICT
Internship at UMC St. Radboud Nijmegen, dept. of Nuclear medicine.
Extension of their internally developed framework for application development. Final applications are used as plug-ins for Siemens Syngo e.soft workstation. Assignment was to extend the framework with tools for 3d visualisation and delineation, using IDL (Interactive Data Language).

Education

2013-2018 Doctor of Philosophy (PhD)
Maastricht University
Clinical Data Science in Radiotherapy
Thesis (DOI): 10.26481/dis.20181128js
2010-2012 Master Medical Informatics
University of Amsterdam
Activities:Member of the course evaluation committee
 IPHIE masterclass
2009-2010 Pre-Master Medical Informatics
University of Amsterdam
Components: Informatics, Care Information, Medicine
2005-2009 Bachelor of ICT
Fontys University of Applied Science
Major: Software Engineering
Minor: Medical Technology

Membership of Professional Associations

Research projects

Period Title Funding organisation Role Description
2022 - present ELSA Lab Armoede en Schulden Ministerie van Binnenlandse Zaken en Koninkrijksrelaties Co-applicant Developing an ethical, legal and societally accepted (ELSA) method to signal people at risk of poverty and/or debts. Including methods for (societally acceptable) interventions, and develop tools to oversee the consequences of new (local) governmental policies.
2022 - present Ketenzorg data analyse Zorginstituut Nederland Co-applicant Developing a prototype for decentralized data analysis on vertically partitioned data (physical therapy and orthopedics), and identifying the roadblocks for scaling such an initiative.
2021 - present EPND IMI Contributor Development of the European Platform for Neurodegenerative Diseases (EPND), specifically in the task of data harmonization and FAIRificiation.
2021 - 2021 SOPHIA IMI Contributor Federeated learning on type 2 Diabetes cohorts in a public-private partnership using OMOP CDM and DataShield.
2020 - 2021 Decentrale kwaliteitsregistraties Zorginstituut Nederland Co-applicant Developing a prototype for decentralized quality registries on horizontally partitioned data, and identifying the roadblocks for scaling such an initiative.
2019 - 2021 FAIRcomml Varian Medical Systems Main Applicant Development and investigation into a software system to describe prediction models, and to link these models to FAIR data. For project results see https://fairmodels.org
2019 - 2020 Verantwoorde Waardecreatie door Data (VWData) Nationale Wetenschaps Agenda (NWA) Contributor Distributed learning on vertical partitioned data sources. Specifically, enabling privacy-preserved analysis on information from a longitudinal cohort study and the national statistics agency (CBS).
2018 - 2019 FAIRsights Varian Medical Systems Main Applicant Development and investigation into a software system to make clinical data FAIR (findable, accessible, interoperable and reusable). For project results see here
2017 - 2021 Limburg Meet (LIME) Provincie Limburg Contributor Development of a communication platform between (medical) institutes in the Limburg region. Institutes are primary care, general hospitals and specialized care facilities. The goal is to minimize the data transfer and duplication needed, while enabling patients to give control over their data.
2016 - 2018 Data Quality Netherlands eScience Center path finder Co-applicant Discovering and developing the need for hospitals to make data available for secondary use.

Teaching and supervision

Courses: PhD students: MSc students: BSc students:

Invited presentations

Published Scientific contributions